I'm running OS X 10.5.8 on an intel duo.
The newest RC crashes immediately on startup - and this has been the case for at least one earlier versions, as well. I believe 1331 is the most recent build I've been able to get to work.
I ran it from terminal to see what that told me, and I got this:
LSOpenFromURLSpec() failed with error -10810 for the file /Users/chris/Downloads/Zelda Classic/Zelda Classic.app.
When I run the executable directly (inside the bundle, not the .app), I get this:
dyld: unknown required load command 0x80000022
Trace/BPT trap