Okay, now that I recall to put the bug icon in...
Open ZQuest, do ANYTHING you want, and hit F2 to save. You get the "error saving" message. I would think the save as dialog should pop up at this point.
Note: the timed save still works properly. I do not follow why that is.
If I load ZQuest, place one tile, and hit F2, I get a Save As dialog box, as expected.
What OS are you using, and are you using any significant command-line options (eg -large)?
613 is the Mac OS X Build. Should I specify that next time I make a topic?
I don't recall setting any options myself, but I think ZQuest is right now set to launch at -large: I see 3 columns for choosing tiles, and I can use buttons instead of Function + Page Down/Up to change the info bar at the bottom.
Maybe it's a Mac issue? Even with -large on I still get prompted to Save As.