They act as if the cursor is one step clockwise. They do work in ZC, though, so it's not my tiles.
(2.5b240) Eye statues point in wrong direction in ZQuest
New info: I was bored, so I was in ZQuest moving my mouse around my dungeon entrance, watching the eyes go (what can I say?). Anyway, I discovered that the eyeball statues act as if they are one tile higher.
By this, I mean that if you have a statue at, say, (4,4), then the statue will either pretend the mouse is 16 pixels lower than it is, or that the statue is 16 pixels higher than it is.
Try it yourself - move your mouse around the tile above a statue. At the bottom, the statue will look down, but at the top, it will look up.
Fixed in the next beta.