I found this flash game yesterday just looking around. Its called Heaven's Key, and its basically a point-and-click game in which your goal is to escape from the room. Its pretty hard, so if you're up for a good challenge, this ought to work. I still haven't finished it though. (Blasted green safe... OPEN ALREADY!!)
Also, its in Japanese, so good luck. (Google or BabbelFish might be a good thing to have handy if you can't read it. (Some text can be copy-pasted from the game.)
Here's the link to it: http://www.ep-melody.com/flash/heavenskey/
If you can't figure something out, just ask and I'll see what I can help with, but I've only reached the green safe right now, so anything past there has me clueless.
Good luck!