Possible Bosses:
1) A drunk guy at Moe's Tavern throwing Beer can's at you!
2) One of the two large, green 1-eyed aliens, perhaps it can slash its long tentacles at you or throw fireballs at you.
3) The large donut guy mascot that came to life, perhaps he can be a boss at throw donuts at you.
4) Itchy, who attacks you with a chainsaw
5) Bart's evil twin
6) A zombie
7) Flying Hellfish, a large red half-fish, half-man sorta being, with large sharp teeth, big muscles, and yellow fins down its back, and a cigar in its mouth.
8) Groundskeeper Willie (with a large rake or a scythe
9) Lunchlady Doris (from the treehouse of horror episode "Nightmare Cafeteria"😉 She attacks using a high-speed electronic cookie dough mixer.
Perhaps more ideas later
And btw, i have the Simpsons episode guide book right here in my room so if u need ideas or don't know who a character is or what he/she looks like, let me know!