Umm...that doesn’t start with Q....
Q -Qix
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Umm...that doesn’t start with Q....
Q -Qix
R - Raiden
Salamander
Thunder Force III
U - Ultima (any of them)
V - Vectorman (not sure if its been used yet, but meh)
W - Watio's Woods
Xande (Final Fantasy 3, the semi final boss because the final boss HAD to come out of nowhere with very little foreshadowing whatsoever)
Y - Yoshi's Island
Z - Zoop
I hated that game, but it starts with Z, so....